Functional Group Inter Conversion
Organic synthesis involves functional group inter conversions. A particular functional group can be converted into other functional group by reacting it with suitable reagents. For example: The carboxylic acid group (-COOH) presents in organic acids can be transformed to a variety of other functional group such as – CH2 – OH, – CONH2, – COCl by treating the acid with LiAlH4, NH3 and SOCl2 respectively.
Some of the important functional group interconversions of Organic compounds are summarised in the below mentioned Flow chart.
Functional group interconversions are systematically discussed since they provide many important routes to amines, notable transformations including: amination of organometallic reagents, reductive aminations involving aldehydes or ketones, reduction of imines, addition of an organometallic reagent to CN bonds.
Some of the important functional groups in biological molecules include: hydroxyl, methyl, carbonyl, carboxyl, amino, phosphate, and sulfhydryl groups. These groups play an important role in the formation of molecules like DNA, proteins, carbohydrates, and lipids.
Compounds containing a nitrogen atom bonded in a hydrocarbon framework are classified as amines. Compounds that have a nitrogen atom bonded to one side of a carbonyl group are classified as amides.
Find free online Chemistry Topics covering a broad range of concepts from research institutes around the world.